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CHEMGENEX TO PRESENT AT THE BIO CEO & INVESTOR CONFERENCE 2005

MELBOURNE, Australia, and MENLO PARK, California U.S.A. (February 23, 2005)

ChemGenex Pharmaceuticals (ASX: CXS) today announced that Greg Collier, Ph.D., chief executive officer of ChemGenex, will be presenting at the BIO CEO & Investor Conference in New York City at 3:00 PM EST on February 23, 2005. The conference brings together CEOs and other senior biotechnology executives, institutional investors and leading biotechnology brokers and analysts to review leading companies and their potential going forward.

Dr. Collier will provide an update on the ChemGenex’s phase 2 clinical programs, Ceflatonin® (HHT) for the treatment of chronic myeloid leukemia and Quinamed® (amonafide dihydrochloride) for the treatment of solid tumors.

Dr Collier will also provide an overview of how the company conducts gene-based drug discovery and development including an update on ChemGenex’s collaborations with Merck KGaA in diabetes and Vernalis in depression. Dr Collier will announce that the company has achieved a research milestone with Vernalis that will result in a milestone payment of A$720,000 (US$568,000).

Dr Collier’s presentation for the BIO CEO & Investor conference and the current ChemGenex shareholder update can be viewed at the company’s website www.chemgenex.com.

Information about the BIO CEO & Investor Conference can be found at www.bio.org.

About ChemGenex Pharmaceuticals Limited

ChemGenex Pharmaceuticals is a pharmaceutical development company dedicated to improving the lives of patients by developing therapeutics in the areas of oncology, diabetes, obesity, and depression. ChemGenex harnesses the power of genomics for target discovery and validation, and in clinical trials to develop more individualized therapeutic outcomes. ChemGenex's lead compound, Ceflatonin®, is currently in phase 2/3 clinical trials for chronic myeloid leukemia and Quinamed® is in phase 2 clinical development for prostate, breast and ovarian cancers. The company has a significant portfolio of anti-cancer, diabetes, obesity and depression programs, several of which have been partnered with international pharmaceutical companies. ChemGenex currently trades on the Australian Stock Exchange under the symbol "CXS" and on NASDAQ under the symbol "CXSP".

Safe Harbor Statement

Certain statements made herein that use the words "estimate", "project", "intend", "expect", "believe", and similar expressions are intended to identify forward-looking statements within the meaning of the US Private Securities Litigation Reform Act of 1995. These forward-looking statements involve known and unknown risks and uncertainties which could cause the actual results, performance or achievements of the company to be materially different from those which may be expressed or implied by such statements, including, among others, risks or uncertainties associated with the development of the company's technology, the ability to successfully market products in the clinical pipeline, the ability to advance promising therapeutics through clinical trials, the ability to establish our fully integrated technologies, the ability to enter into additional collaborations and strategic alliances and expand current collaborations and obtain milestone payments, the suitability of internally discovered genes for drug development, the ability of the company to meet its financial requirements, the ability of the company to protect its proprietary technology, potential limitations on the company's technology, the market for the company's products, government regulation in Australia and the United States, changes in tax and other laws, changes in competition and the loss of key personnel. These statements are based on our management's current expectations and are subject to a number of uncertainties that could change the results described in the forward-looking statements.  Investors should be aware that there are no assurances that results will not differ from those projected.


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